Social cognitive and neural mechanisms of food choice under the influence of food-related information

Food is the fuel of life. As such food stimuli are intensively processed by the human brain and the consequences of these processes, resulting in our food choice, have an essential impact on our life. Research suggested that food choice is largely guided by predominantly learned preference, and is likely to be influenced by information regarding the food (e.g., nutritional value) as well as by learned beliefs and associations (e.g., between a given food and its health value). This project aims at understanding at both behavioral and neural levels how these non-physiological factors might influence the food/drink choice and how they can be modified to improve our choice. Chapter 1 includes the literature review on 1) how semantic information influences implicit/explicit associations toward food/drink, 2) the predictive validity implicit/explicit associations on food/drink choice, 3) the behavioral and neural evidence of changing associations, choices, and impulsivity control toward food/drink by implementing a conditioning paradigm (e.g. evaluative conditioning). The motivation and the objectives of my Ph.D. project are also presented here. Chapter 2 contains Study 1 (Experiment 1 and 2). The first aim of the thesis is to understand how the association between a certain food and different concepts may guide our choices. This is addressed in Experiment 1 where I investigated how our choices can be predicted by preference and/or implicit associations between different constructs of interest (e.g., social status) and coffee and/or tea. People\u2019s self-report preference, implicit and explicit associations between different social constructs and tea/coffee were measured. Results based on 22 Italian healthy adults indicate that they possess strong implicit associations between tea and low social status, and this association significantly predicted choice of tea. The second aim of the thesis is to investigate whether the associations between food/drink and certain constructs can be changed through a classical learning paradigm, evaluative conditioning (EC), in which the associations between target drinks/food and food-related information was manipulated. This approach allowed us to investigate a possible strategy of intervention that could improve drink/food choices. This is addressed in Experiment 2 whereby a within-subject design is employed with participants going through both EC-condition and control condition. Results based on 68 healthy adults show that the implicit associations between tea and high-social-status, as well as the preference towards tea, significantly increase after EC. Most importantly, the difference in implicit associations across conditions significantly predict the difference in choices of tea between conditions, indicating that changes in implicit associations determine changes in choice. Chapter 3 is dedicated to the third aim which is to identify the neural mechanisms underlying the changes in association after EC between foods and the concepts of healthiness and sustainability. To this end changes in neural markers were related to changes in food choice as well as personal eating habits and individual difference in restraint eating and impulsive behavior. In Study 2, I experimentally strengthened the association between the concept of unhealthiness/unsustainability and heavily-processed food, and between healthiness/sustainability and minimally-processed food. A semantic congruency task combined with the Electroencephalography (EEG) technique was used to investigate changes in neural activity of the N400 in incongruent trials. Results on 18 healthy adults derived by comparing neural signatures of incongruent trials between conditions demonstrated that the magnitude of the N400 in left dorsal lateral prefrontal cortex (DLPFC) for minimally-processed high-calorie food significantly increased after EC. Thus, EC can be considered as an effective method to strengthen the semantic association between foods and a given concept, indexed by the change of neural signature tracking the semantic conflict. This increased magnitude also positively correlated with the Barratt Impulsiveness Scale score, indicating that the more impulsive a person is, the greater the change in magnitude of the N400. Chapter 4 is devoted to address the fourth aim of the thesis that is to understand whether control of impulsivity over unhealthy food choice can be improved through the evaluative priming (EP) that is a variation of EC used in Study 2. Thus in Study 3, 15 healthy adults went through a pre-EP and a post-EP test including a Go/NoGo task combined with EEG. During EP, an increased subjective liking was found for Minimally-Processed Low-Calorie food images in evaluative block. For GNG tasks, at neural level, the averaged amplitude at left DLPFC for food images with evaluative priming was more negative in post-EP than in pre-EP GNG task. More negative N200 amplitudes were consistently found at left DLPFC in post-EP GNG task for Heavily-Processed Low-Calorie food as well as for Minimally-Processed Low-Calorie food. The behavioral and neural evidence showed the improvement of self-control towards food stimuli through evaluative priming. The possible role of left dorsal lateral prefrontal region in online value modulation and in integrating the stimulus feature with related information was identified, suggesting the self-control process based on deliberated thinking with symbolic representations and information operations. In Chapter 5 I summarized and discussed the main findings of my thesis. In short, my project provides the basic roadmap for understanding how food/drink related information affects cognitive and neural underpinnings of food/drink choices. Indeed, choices can be improved through modifying associations between food/drink and related information and thus healthy diets are encouraged. These results provide a potentially interesting research avenue well as possible interventions to modify and improve food/drink choices that could possibly be applied to individuals with eating disorders

The role of associative learning in healthy and sustainable food evaluations : An event-related potential study

Individuals in industrialized societies frequently include processed foods in their diet. However, overconsumption of heavily processed foods leads to imbalanced calorie intakes as well as negative health consequences and environmental impacts. In the present study, normal-weight healthy individuals were recruited in order to test whether associative learning (Evaluative Conditioning, EC) could strengthen the association between food-types (minimally processed and heavily processed foods) and concepts (e.g., healthiness), and whether these changes would be reflected at the implicit associations, at the explicit ratings and in behavioral choices. A Semantic Congruency task (SC) during electroencephalography recordings was used to examine the neural signature of newly acquired associations between foods and concepts. The accuracy after EC towards minimally processed food (MP-food) in the SC task significantly increased, indicating strengthened associations between MP-food and the concept of healthiness through EC. At the neural level, a more negative amplitude of the N400 waveform, which reflects semantic incongruency, was shown in response to MP-foods paired with the concept of unhealthiness in proximity of the dorsal lateral prefrontal cortex (DLPFC). This implied the possible role of the left DLPFC in changing food representations by integrating stimuli’s features with existing food-relevant information. Finally, the N400 effect was modulated by individuals’ attentional impulsivity as well as restrained eating behavior

Significant association of hematinic deficiencies and high blood homocysteine levels with burning mouth syndrome

Background/PurposeBurning mouth syndrome (BMS) is characterized by a burning sensation of the oral mucosa in the absence of clinically apparent mucosal alterations. In this study, we evaluated whether there was an intimate association of the deficiency of hemoglobin (Hb), iron, vitamin B12, or folic acid; high blood homocysteine level; and serum gastric parietal cell antibody (GPCA) positivity with BMS.MethodsBlood Hb, iron, vitamin B12, folic acid, and homocysteine concentrations and the serum GPCA level were measured in 399 BMS patients and compared with the corresponding levels in 399 age- and sex-matched healthy control individuals.ResultsWe found that 89 (22.3%), 81 (20.3%), 10 (2.5%), and six (1.5%) BMS patients had deficiencies of Hb (men: <13 g/dL, women: <12 g/dL), iron (<60 μg/dL), vitamin B12 (<200 pg/mL), and folic acid (<4 ng/mL), respectively. Moreover, 89 (22.3%) BMS patients had abnormally high blood homocysteine level and 53 (13.3%) had serum GPCA positivity. BMS patients had a significantly higher frequency of Hb, iron, or vitamin B12 deficiency; of abnormally elevated blood homocysteine level; or of serum GPCA positivity than the healthy control group (all p < 0.001 except for vitamin B12 deficiency, for which p = 0.004). However, no significant difference in frequency of folic acid deficiency (p = 0.129) was found between BMS patients and healthy control individuals.ConclusionWe conclude that there is a significant association of deficiency of Hb, iron, and vitamin B12; abnormally high blood homocysteine level; and serum GPCA positivity with BMS

Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

Search for stop and higgsino production using diphoton Higgs boson decays

Results are presented of a search for a "natural" supersymmetry scenario with gauge mediated symmetry breaking. It is assumed that only the supersymmetric partners of the top-quark (stop) and the Higgs boson (higgsino) are accessible. Events are examined in which there are two photons forming a Higgs boson candidate, and at least two b-quark jets. In 19.7 inverse femtobarns of proton-proton collision data at sqrt(s) = 8 TeV, recorded in the CMS experiment, no evidence of a signal is found and lower limits at the 95% confidence level are set, excluding the stop mass below 360 to 410 GeV, depending on the higgsino mass

Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation

One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced. Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good